Natural Remedies R&D Center caters to both Animal Health Care as well as Human Health Care business and provides a platform for developing innovative products. It is well equipped with latest instruments to ensure and maintain the world class standards of health and safety, improved efficacy and increased productivity.
All our products have gone through various levels of checks to ensure best efficacy, safety and palatability.
The Phytochemistry laboratory develops commercially viable processes for the optimum extraction of medicinal plants where active constituents (markers) are known. The plant extracts generated thereof are standardized to contain known amount(s) of biologically active constituent(s). For plants where active / markers are not known, bioactivity guided fractionations are undertaken and active / biomarkers are isolated for the purpose of standardization.
Chromatographic techniques like column, flash, MPLC, Preparative HPLC are employed for isolating constituents. The isolated single chemical entities are thoroughly characterized using the conventional spectroscopic (UV, IR, NMR & Mass spectroscopy) and chromatographic techniques.
In the discovery cycle, for the predictions of the effects that a drug will display, measurement of its specific functional response induced in a biological system ‘a bioassay’ is required. A bioassay is thus an essential tool for research and development. Bioassays based on the in vitro responses of enzymes or stable cell lines are commonly the assay systems of choice for this purpose. These bio-assays are rapid, reproducible, economical, sample hungry.
We have standardized and routinely perform more than 125 in-vitro assays relevant to selection and optimization of new drug candidates using specialized assay technologies based on different detection modes like Absorbance (colorimetric, ELISA), Luminescence and Fluorescence (Fluorescence Intensity, Fluorescence Polarization, Time-Resolved Fluorescence etc) in 96 and 384 well formats. The simple, rapid and cost-effective nature of bioassays facilitates screening of a large number of samples. Plants effective in in-vitro assays are developed into prototypes, which ultimately get tested in in-vivo assays.
Apart from new product development, bio-assays can be effectively be used for screening campaigns, bio-activity guided fractionation, compatibility studies, and stability studies.
This laboratory is specialized to conduct microbiological quality control and antimicrobial screening of herbal products. Various analytical procedures in this laboratory are tailor made to suit herbal products and are in accordance with USP method.
The Department is comprised of three major divisions: In vitro, In vivo and Clinical Pharmacology. Presently, the department includes a team of competent scientists from various disciplines like pharmacology, biochemistry, and other allied life sciences. The department is committed to the development of a strong herbal research environment within and between various other divisions. The divisions are well equipped with sophisticated instruments for in vitro pharmacological assays and a central animal facility registered under Committee for the Purpose of Control and Supervision of Experiments on Animals (CPCSEA) for efficacy and toxicity studies.
Evaluation of herbs for therapeutic use and safety assessment of mono- and polyherbal formulations are the core areas of focus. The team is engaged in evaluating a range of products for veterinary and human health care, to cater to the needs of livestock and human segments.
The Department is comprised of three major divisions: In vitro, In vivo and Clinical Pharmacology. Presently, the department includes a team of competent scientists from various disciplines like pharmacology, biochemistry, and other allied life sciences. The department is committed to the development of a strong herbal research environment within and between various other divisions. The divisions are well equipped with sophisticated instruments for in vitro pharmacological assays and a central animal facility registered under Committee for the Purpose of Control and Supervision of Experiments on Animals (CPCSEA) for efficacy and toxicity studies.
This group is already engaged in development of analytical monographs for more than one dozen Indian Medicinal Plants for the forthcoming Indian Pharmacopoeia along with Central Indian Pharmacopoeia Laboratory (C I P L) (Govt. of India), Ghaziabad. This lab routinely uses specific and non-specific bio-assays wherever possible in order to achieve bio-standardization.
Evaluation of herbs for therapeutic use and safety assessment of mono- and polyherbal formulations are the core areas of focus. The team is engaged in evaluating a range of products for veterinary and human health care, to cater to the needs of livestock and human segments.
Formulation and Development is one of the key department in R&D. The main objective of this department is to develop new formulations in different dosage forms for Human and Veterinary use. The lab is equipped with modern infrastructure for carrying out formulation studies. The lab has developed first herbal aerosol spray for veterinary use in India.
As a manufacturer of herbal products, we consume more than 500 tones of crude drug / annum. This requirement of crude drugs is almost wholly fulfilled by collections from the wild / forests. But it is not possible to derive all this material from the wild, because the population of wild medicinal plants is growing thinner day by day due to over exploitation and indiscriminate deforestation. Moreover, because of insufficient raw material ( poor availability ), the price of material shoots up. These are thus valid reasons for cultivating medicinal plants.
We undertake Contract Farming of selected Indian medicinal plants through interested farmers and offer cent percent buy back. Our agriculture farming is stipulated under strictly defined conditions as are specific for each plant. We provide the planting material and complete cultivation plan to farmers and to supervise the proper implementation of plan we have groomed a team of Agriculture Graduates. Our agronomy team has covered approximately 1500 acres of land under contract farming in South India through buy back agreements.
Through contract farming we have done good R&D work to formulate Good Agricultural Practices, which includes proper selection and identification, propagation methods, cultivation techniques, harvesting, step-wise quality control of raw material up to processing stage, post-harvest treatment, storage and safety.
For more details contact: agronomy@naturalremedy.com